孕期母体补充碘的效果。
Effects of maternal iodine supplementation during pregnancy.
作者信息
Pharoah P O, Connolly K J
机构信息
Department of Public Health, University of Liverpool.
出版信息
Arch Dis Child. 1991 Jan;66(1):145-7. doi: 10.1136/adc.66.1.145.
Abstract
Reduced maternal thyroid hormone concentrations during pregnancy can adversely affect fetal neurological development. In the context of national iodine supplementation programmes, concern has been expressed over the theoretical possibility that iodine supplementation during pregnancy might adversely affect fetal development as a result of maternal thyroid inhibition from the Wolff-Chaikoff effect. In a double blind controlled trial in five villages in Papua New Guinea, several measures of motor and cognitive function showed no significant differences at either age 11 or 15 years between those children whose mothers had received supplementary iodine during pregnancy and the control children whose mothers had received the placebo.
摘要
孕期母体甲状腺激素浓度降低会对胎儿神经发育产生不利影响。在国家碘补充计划的背景下，有人担心孕期补碘可能因沃尔夫-柴可夫效应导致母体甲状腺受抑制，从而对胎儿发育产生不利影响。在巴布亚新几内亚五个村庄进行的一项双盲对照试验中，在11岁和15岁时，母亲孕期接受补碘的儿童与母亲接受安慰剂的对照儿童在多项运动和认知功能指标上均未显示出显著差异。
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Dev Med Child Neurol. 1981 Feb;23(1):76-82. doi: 10.1111/j.1469-8749.1981.tb08448.x.
2
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3
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