从鼯鼠粪便中提取的抗血栓黄酮类化合物。

Antithrombotic flavonoids from the faeces of Trogopterus xanthipes.

机构信息

Jiangsu Key Laboratory for TCM Formulae Research, College of Pharmacy, Nanjing University of Chinese Medicine, P.R. China.

出版信息

Nat Prod Res. 2010 Nov;24(19):1843-9. doi: 10.1080/14786419.2010.482057.

DOI:10.1080/14786419.2010.482057

PMID:21104530

Abstract

Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavonoid glycosides in Trogopterus faeces.

摘要

对鼯鼠粪便的化学研究导致了七种类黄酮的分离。它们的结构通过化学和光谱分析阐明。在抗凝测定中，三种山柰酚咖啡酰鼠李糖苷具有显著的抗凝血酶活性。这是关于鼯鼠粪便中存在类黄酮糖苷的首次报道。