Oxford Cancer Centre, Department of Gynaecologic Oncology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom.
Eur J Surg Oncol. 2010 Apr;36(4):335-9. doi: 10.1016/j.ejso.2009.11.006. Epub 2009 Dec 1.
Aggressive angiomyxoma was identified as a distinct clinicopathologic entity in 1983 and since then fewer than 250 cases of these rare tumors have been reported in world literature. These tumors usually arise in the pelvis and perineal regions, most often in women of the reproductive age group; however a few cases of its occurrence outside the pelvis have also been reported.
We report a series of 7 women treated in our institute in the last 8 years. Relevant literature on aggressive angiomyxoma was looked at and various management options reviewed.
Aggressive angiomyxomas are locally aggressive, notorious for local recurrence and extremely rare to metastasize. While surgery remains the mainstay of treatment, there has been a definite shift towards less radical forms of excision, over the years. Various adjuvant treatment modalities have also been tried to reduce tumor recurrence.
侵袭性血管黏液瘤于 1983 年被确定为一种独特的临床病理实体，此后，世界文献中仅报道了不到 250 例此类罕见肿瘤。这些肿瘤通常发生在骨盆和会阴区域，大多数发生在育龄期妇女；但也有少数发生在骨盆外的病例报道。
我们报告了过去 8 年在我们研究所治疗的 7 名女性患者。查阅了关于侵袭性血管黏液瘤的相关文献，并回顾了各种治疗选择。
侵袭性血管黏液瘤具有局部侵袭性，局部复发率高，极为罕见转移。虽然手术仍然是主要的治疗方法，但多年来，已经明确转向更保守的切除形式。还尝试了各种辅助治疗方法来降低肿瘤复发率。
