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本文引用的文献

1
Computing has changed biology--biology education must catch up.计算机技术已经改变了生物学——生物学教育必须跟上步伐。
Science. 2009 Jul 31;325(5940):541-2. doi: 10.1126/science.1173876.
2
Target discovery from data mining approaches.基于数据挖掘方法的靶点发现
Drug Discov Today. 2009 Feb;14(3-4):147-54. doi: 10.1016/j.drudis.2008.12.005. Epub 2009 Jan 20.
3
A review of bioinformatics education in Germany.德国生物信息学教育综述。
Brief Bioinform. 2008 May;9(3):232-42. doi: 10.1093/bib/bbn006. Epub 2008 Mar 1.
4
Advanced sequencing technologies and their wider impact in microbiology.先进的测序技术及其在微生物学中的广泛影响。
J Exp Biol. 2007 May;210(Pt 9):1518-25. doi: 10.1242/jeb.001370.
5
Integration of omics data: how well does it work for bacteria?组学数据整合:对细菌的效果如何?
Mol Microbiol. 2006 Dec;62(5):1239-50. doi: 10.1111/j.1365-2958.2006.05453.x. Epub 2006 Oct 16.
6
Back to the future: education for systems-level biologists.回到未来:面向系统生物学领域生物学家的教育
Nat Rev Mol Cell Biol. 2006 Nov;7(11):829-32. doi: 10.1038/nrm2023. Epub 2006 Sep 20.
7
An interdepartmental Ph.D. program in computational biology and bioinformatics: the Yale perspective.计算生物学与生物信息学跨部门博士项目:耶鲁大学的视角
J Biomed Inform. 2007 Feb;40(1):73-9. doi: 10.1016/j.jbi.2006.02.008. Epub 2006 Mar 6.
8
Biomedical informatics training at Stanford in the 21st century.21世纪斯坦福大学的生物医学信息学培训。
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9
The model organism as a system: integrating 'omics' data sets.作为一个系统的模式生物:整合“组学”数据集。
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10
Bioinformatics education--perspectives and challenges.生物信息学教育——观点与挑战。
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一个针对大学生的最低技能要求建议,以满足“组学”时代的信息学需求和挑战。

A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the "-omics" era.

机构信息

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore.

出版信息

BMC Genomics. 2009 Dec 3;10 Suppl 3(Suppl 3):S36. doi: 10.1186/1471-2164-10-S3-S36.

DOI:10.1186/1471-2164-10-S3-S36
PMID:19958501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2788390/
Abstract

BACKGROUND

The development of high throughput experimental technologies have given rise to the "-omics" era where terabyte-scale datasets for systems-level measurements of various cellular and molecular phenomena pose considerable challenges in data processing and extraction of biological meaning. Moreover, it has created an unmet need for the effective integration of these datasets to achieve insights into biological systems. While it has increased the demand for bioinformatics experts who can interface with biologists, it has also raised the requirement for biologists to possess a basic capability in bioinformatics and to communicate seamlessly with these experts. This may be achieved by embedding in their undergraduate and graduate life science education, basic training in bioinformatics geared towards acquiring a minimum skill set in computation and informatics.

RESULTS

Based on previous attempts to define curricula suitable for addressing the bioinformatics capability gap, an initiative was taken during the Workshops on Education in Bioinformatics and Computational Biology (WEBCB) in 2008 and 2009 to identify a minimum skill set for the training of future bioinformaticians and molecular biologists with informatics capabilities. The minimum skill set proposed is cross-disciplinary in nature, involving a combination of knowledge and proficiency from the fields of biology, computer science, mathematics and statistics, and can be tailored to the needs of the "-omics".

CONCLUSION

The proposed bioinformatics minimum skill set serves as a guideline for biology curriculum design and development in universities at both the undergraduate and graduate levels.

摘要

背景

高通量实验技术的发展催生了“组学”时代,在这个时代,对各种细胞和分子现象进行系统水平测量的兆字节级数据集在数据处理和提取生物学意义方面带来了相当大的挑战。此外,这也产生了有效整合这些数据集以深入了解生物系统的未满足需求。虽然这增加了对能够与生物学家合作的生物信息学专家的需求,但也提高了生物学家在生物信息学方面的基本能力要求,并与这些专家进行无缝沟通的要求。这可以通过在本科和研究生生命科学教育中嵌入基本的生物信息学培训来实现,培训的目标是获得计算和信息学方面的最低技能集。

结果

基于之前尝试定义适合解决生物信息学能力差距的课程的努力,在 2008 年和 2009 年的生物信息学和计算生物学教育研讨会上,我们提出了一项倡议,旨在确定未来的生物信息学家和具有信息学能力的分子生物学家的最低技能集。拟议的最低技能集具有跨学科性质,涉及生物学、计算机科学、数学和统计学领域的知识和熟练程度的结合,并且可以根据“组学”的需求进行调整。

结论

所提出的生物信息学最低技能集可作为大学本科和研究生生物课程设计和开发的指南。