MASE Masaji, CHUUJOU Masaki, INOUE Toshikazu, NAKAMURA Kikuyasu, YAMAGUCHI Shigeo, IMADA Tadao
National Institute of Animal Health, Tsukuba, Ibaraki, Japan.
J Vet Med Sci. 2009 Nov;71(11):1455-8. doi: 10.1292/jvms.001455.
We genetically characterized fowl adenoviruses (serotype 4 FAdV, FAdV-4) isolated from chickens with hydropericardium syndrome (HPS) in Japan by the polymerase chain reaction (PCR) method coupled with direct sequencing. Phylogenetic analysis based on the part of the hexon gene that included the L1 region revealed that all FAdV-4 isolates from chickens with HPS in Japan were identical and were distinguished completely from the cluster including FAdV strains from chickens with HPS in India and Pakistan. This suggested that FAdV-4 from the HPS chickens in India and Pakistan was derived from a common ancestor, but the origin of the FAdV-4 from the HPS chickens in Japan was completely different.
我们通过聚合酶链反应（PCR）方法结合直接测序，对从日本患有心包积水综合征（HPS）的鸡中分离出的禽腺病毒（血清型4 FAdV，FAdV-4）进行了基因特征分析。基于包含L1区域的六邻体基因部分进行的系统发育分析表明，日本所有从患有HPS的鸡中分离出的FAdV-4毒株均相同，并且与包括来自印度和巴基斯坦患有HPS的鸡的FAdV毒株的簇完全区分开来。这表明印度和巴基斯坦患有HPS的鸡的FAdV-4源自共同祖先，但日本患有HPS的鸡的FAdV-4的起源则完全不同。
