非快速眼动睡眠的缓慢（<1 Hz）节律：三个主要振荡器之间的对话。
The slow (<1 Hz) rhythm of non-REM sleep: a dialogue between three cardinal oscillators.
机构信息
School of Biosciences, Cardiff University, Cardiff, UK.
出版信息
Nat Neurosci. 2010 Jan;13(1):9-17. doi: 10.1038/nn.2445. Epub 2009 Dec 6.
Abstract
The slow (<1 Hz) rhythm, the most important electroencephalogram (EEG) signature of non-rapid eye movement (NREM) sleep, is generally viewed as originating exclusively from neocortical networks. Here we argue that the full manifestation of this fundamental sleep oscillation in a corticothalamic module requires the dynamic interaction of three cardinal oscillators: one predominantly synaptically based cortical oscillator and two intrinsic, conditional thalamic oscillators. The functional implications of this hypothesis are discussed in relation to other EEG features of NREM sleep, with respect to coordinating activities in local and distant neuronal assemblies and in the context of facilitating cellular and network plasticity during slow-wave sleep.
摘要
慢波（<1 Hz）节律是非快速眼动（NREM）睡眠最重要的脑电图（EEG）特征，通常被认为仅源自新皮层网络。在这里，我们认为在皮质丘脑模块中充分表现出这种基本睡眠振荡需要三个主要振荡器的动态相互作用：一个主要基于突触的皮质振荡器和两个内在的、条件性的丘脑振荡器。该假设的功能意义将在与 NREM 睡眠的其他 EEG 特征有关的内容中进行讨论，涉及到协调局部和远程神经元集合的活动，以及在慢波睡眠期间促进细胞和网络可塑性的问题。
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