百日咳毒素S1亚基序列的进一步分析。
Further analysis of the sequence of the S1 subunit of pertussis toxin.
作者信息
Pizza M, Bugnoli M, Pucci P, Siciliano R, Marino G, Rappuoli R
机构信息
Sclavo Research Center, Siena, Italy.
出版信息
Infect Immun. 1991 Mar;59(3):1177-9. doi: 10.1128/iai.59.3.1177-1179.1991.
Abstract
The two published sequences of the pertussis toxin operon differ in 3 bp in the S1 subunit gene. In this report, we provide evidence that Bordetella pertussis strains are able to produce active pertussis toxin only when they contain one of the two possible nucleotide sequences.
摘要
百日咳毒素操纵子的两个已发表序列在S1亚基基因中有3个碱基对的差异。在本报告中，我们提供了证据表明，百日咳博德特氏菌菌株只有在包含两种可能的核苷酸序列之一时才能产生活性百日咳毒素。
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