Centre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
J Allergy Clin Immunol. 2009 Dec;124(6):1251-8.e23. doi: 10.1016/j.jaci.2009.10.009.
In 1999, The International Study of Asthma and Allergies in Childhood (ISAAC) Phase One reported the prevalence of eczema symptoms in 715,033 children from 154 centers in 56 countries by using standardized epidemiologic tools.
To update the world map of eczema prevalence after 5 to 10 years (ISAAC Phase Three) and include additional data from over 100 new centers.
Cross-sectional surveys using the ISAAC questionnaire on eczema symptoms were completed by adolescents 13 to 14 years old and by parents of children 6 to 7 years old. Current eczema was defined as an itchy flexural rash in the past 12 months and was considered severe eczema if associated with 1 or more nights per week of sleep disturbance.
For the age group 6 to 7 years, data on 385,853 participants from 143 centers in 60 countries showed that the prevalence of current eczema ranged from 0.9% in India to 22.5% in Ecuador, with new data showing high values in Asia and Latin America. For the age group 13 to 14 years, data on 663,256 participants from 230 centers in 96 countries showed prevalence values ranging from 0.2% in China to 24.6% in Columbia with the highest values in Africa and Latin America. Current eczema was lower for boys than girls (odds ratio, 0.94 and 0.72 at ages 6 to 7 years and 13 to 14 years, respectively).
ISAAC Phase Three provides comprehensive global data on the prevalence of eczema symptoms that is essential for public health planning. New data reveal that eczema is a disease of developing as well as developed countries.
1999 年，国际儿童哮喘和过敏研究（ISAAC）第一阶段报告了来自 56 个国家的 154 个中心的 715033 名儿童的湿疹症状流行率，使用了标准化的流行病学工具。
更新 5 至 10 年后（ISAAC 第三阶段）的全球湿疹流行率图，并纳入来自 100 多个新中心的额外数据。
使用 ISAAC 湿疹症状问卷对 13 至 14 岁的青少年和 6 至 7 岁的儿童的父母进行了横断面调查。当前湿疹被定义为过去 12 个月内有瘙痒的屈侧皮疹，如果每周有 1 个或更多晚上睡眠受到干扰，则认为是严重湿疹。
对于 6 至 7 岁年龄组，来自 60 个国家的 143 个中心的 385853 名参与者的数据显示，当前湿疹的患病率从印度的 0.9%到厄瓜多尔的 22.5%不等，新数据显示亚洲和拉丁美洲的患病率较高。对于 13 至 14 岁年龄组，来自 96 个国家的 230 个中心的 663256 名参与者的数据显示，患病率从中国的 0.2%到哥伦比亚的 24.6%不等，非洲和拉丁美洲的患病率最高。当前湿疹在男孩中比女孩中更为少见（比值比，6 至 7 岁和 13 至 14 岁时分别为 0.94 和 0.72）。
ISAAC 第三阶段提供了关于湿疹症状流行率的全球综合数据，这对公共卫生规划至关重要。新数据显示，湿疹是发展中国家和发达国家的一种疾病。
