Yuan Si-Ming, Jiang Hui-Qing, Hong Zhi-Jian, Wang Xiu-Kun, Wang Jun, Hu Xin-Bao
Department of Plastic and Burn Surgery, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing 210002, China.
Zhonghua Zheng Xing Wai Ke Za Zhi. 2009 Sep;25(5):343-6.
To evaluate the therapeutic effect of retained copper wires combined with pingyangmycin (PYM) injection for complicated cavernous venous malformation.
The location of venous malformation was detected by physical examination and MRI. The copper wires in 0.2 mm width were used to puncture the lesion repeatedly and retained in the lesion to form a net. After that, 8 mg PYM was injected into the residue malformed veins. 8-10 days later, the copper wires were taken out and necrotic tissue was squeezed out. The wounds of punctual holes healed through dressing. The patients received postoperative MRI to evaluate the therapeutic effect.
From Jan. 2002 to Dec. 2008, 45 cases were treated. The patients were followed up for 1-3 years. 51.1% (23/45) of the lesions shrinked markedly or even disappeared. 42.2% (19/45) of the lesions reduced. 6.67% (3/45) of the lesions didn't change. There was no complication like invasive infection.
It is very effective to treat complicated cavernous venous malformation with retained copper wires combined with pingyangmycin injection.
评估留置铜丝联合平阳霉素（PYM）注射治疗复杂海绵状静脉畸形的疗效。
通过体格检查和磁共振成像（MRI）检测静脉畸形的位置。使用宽度为0.2毫米的铜丝反复穿刺病变并留置在病变内形成网。之后，将8毫克PYM注入残留的畸形静脉。8至10天后，取出铜丝并挤出坏死组织。穿刺孔伤口通过换药愈合。患者术后接受MRI评估治疗效果。
2002年1月至2008年12月，共治疗45例患者。患者随访1至3年。51.1%（23/45）的病变明显缩小甚至消失。42.2%（19/45）的病变缩小。6.67%（3/45）的病变无变化。无侵袭性感染等并发症。
留置铜丝联合平阳霉素注射治疗复杂海绵状静脉畸形非常有效。
