• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Breast tumour stroma is a prognostic indicator and target for therapy.

作者信息

Howell Anthony, Landberg Goran, Bergh Jonas

机构信息

Breakthrough Breast Cancer Research Unit, Paterson Institute for Cancer Research, University of Manchester, The Christie NHS Foundation Trust, University Hospital of South Manchester, Manchester M20 4BX, UK.

出版信息

Breast Cancer Res. 2009;11 Suppl 3(Suppl 3):S16. doi: 10.1186/bcr2435. Epub 2009 Dec 18.

DOI:10.1186/bcr2435
PMID:20030867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2797696/
Abstract
摘要

相似文献

1
Breast tumour stroma is a prognostic indicator and target for therapy.乳腺肿瘤基质是一种预后指标和治疗靶点。
Breast Cancer Res. 2009;11 Suppl 3(Suppl 3):S16. doi: 10.1186/bcr2435. Epub 2009 Dec 18.
2
Expression of caveolin-1 in breast cancer stroma as a potential prognostic biomarker of survival and progression: a meta-analysis.小窝蛋白-1在乳腺癌基质中的表达作为生存和进展的潜在预后生物标志物：一项荟萃分析
Wien Klin Wochenschr. 2017 Aug;129(15-16):558-563. doi: 10.1007/s00508-017-1173-3. Epub 2017 Mar 31.
3
A genomic ruler to assess oncogenic transition between breast tumor and stroma.一种用于评估乳腺肿瘤和基质之间致癌转化的基因组标尺。
PLoS One. 2018 Oct 16;13(10):e0205602. doi: 10.1371/journal.pone.0205602. eCollection 2018.
4
Tumour infiltrating lymphocytes and stromal CD68 in early stage HER2 positive breast cancer.早期HER2阳性乳腺癌中的肿瘤浸润淋巴细胞和基质CD68
J Clin Pathol. 2016 Jun;69(6):552-5. doi: 10.1136/jclinpath-2015-203493. Epub 2016 Mar 7.
5
Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment.了解沃伯格效应和基质窖蛋白-1作为致命肿瘤微环境标志物的预后价值。
Breast Cancer Res. 2011 Jul 8;13(4):213. doi: 10.1186/bcr2892.
6
Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer.趋化因子CXCL14在肿瘤基质中的表达是乳腺癌患者生存的独立标志物。
Br J Cancer. 2016 May 10;114(10):1117-24. doi: 10.1038/bjc.2016.104. Epub 2016 Apr 26.
7
Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer.基质小窝蛋白-1的表达可能是乳腺癌侵袭性行为的一个预测指标。
Pathol Oncol Res. 2018 Jan;24(1):59-65. doi: 10.1007/s12253-017-0212-8. Epub 2017 Feb 24.
8
Prognostic and functional role of subtype-specific tumor-stroma interaction in breast cancer.乳腺癌中亚型特异性肿瘤-基质相互作用的预后和功能作用。
Mol Oncol. 2017 Oct;11(10):1399-1412. doi: 10.1002/1878-0261.12107. Epub 2017 Aug 22.
9
Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers.将患者来源的异种移植模型的全转录组分析作为一种识别肿瘤和基质特异性生物标志物的工具。
Oncotarget. 2016 Apr 12;7(15):20773-87. doi: 10.18632/oncotarget.8014.
10
Prognostic impact of the cancer stem cell related markers ALDH1 and EZH2 in triple negative and basal-like breast cancers.癌症干细胞相关标志物 ALDH1 和 EZH2 在三阴性和基底样乳腺癌中的预后影响。
Pathology. 2012 Jun;44(4):303-12. doi: 10.1097/PAT.0b013e3283534bcb.

引用本文的文献

1
Midkine as a driver of age-related changes and increase in mammary tumorigenesis.Midkine 作为与年龄相关的变化和乳腺肿瘤发生增加的驱动因素。
Cancer Cell. 2024 Nov 11;42(11):1936-1954.e9. doi: 10.1016/j.ccell.2024.09.002. Epub 2024 Oct 3.
2
Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer.靶向治疗调节癌症相关成纤维细胞的分泌组以诱导 HER2 阳性乳腺癌的耐药性。
Int J Mol Sci. 2021 Dec 10;22(24):13297. doi: 10.3390/ijms222413297.
3
Breast Mammographic Density: Stromal Implications on Breast Cancer Detection and Therapy.乳腺钼靶密度：基质对乳腺癌检测与治疗的影响
J Clin Med. 2020 Mar 12;9(3):776. doi: 10.3390/jcm9030776.
4
Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.乳腺癌临床前模型的特征揭示了巨噬细胞极化的特定模式。
PLoS One. 2016 Jul 7;11(7):e0157670. doi: 10.1371/journal.pone.0157670. eCollection 2016.
5
Methods of Cell Propulsion through the Local Stroma in Breast Cancer.乳腺癌中细胞通过局部基质推进的方法。
Int J Breast Cancer. 2014;2014:197480. doi: 10.1155/2014/197480. Epub 2014 Apr 7.
6
Endorepellin evokes autophagy in endothelial cells.内皮细胞中的内源性排斥素可引发自噬。
J Biol Chem. 2014 Jun 6;289(23):16114-28. doi: 10.1074/jbc.M114.556530. Epub 2014 Apr 15.
7
Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.核心聚糖蛋白可影响三阴性原位乳腺癌异种移植模型肿瘤微环境的整体基因表达谱。
PLoS One. 2012;7(9):e45559. doi: 10.1371/journal.pone.0045559. Epub 2012 Sep 19.
8
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.激素和内分泌干扰化学品：低剂量效应和非单调剂量反应。
Endocr Rev. 2012 Jun;33(3):378-455. doi: 10.1210/er.2011-1050. Epub 2012 Mar 14.
9
Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment.了解沃伯格效应和基质窖蛋白-1作为致命肿瘤微环境标志物的预后价值。
Breast Cancer Res. 2011 Jul 8;13(4):213. doi: 10.1186/bcr2892.
10
Microenvironmental influences that drive progression from benign breast disease to invasive breast cancer.推动良性乳腺疾病向浸润性乳腺癌进展的微环境影响。
J Mammary Gland Biol Neoplasia. 2010 Dec;15(4):389-97. doi: 10.1007/s10911-010-9195-8. Epub 2010 Dec 16.

本文引用的文献

1
Environment-mediated drug resistance: a major contributor to minimal residual disease.环境介导的耐药性：微小残留病的主要促成因素。
Nat Rev Cancer. 2009 Sep;9(9):665-74. doi: 10.1038/nrc2714. Epub 2009 Aug 20.
2
First results for agents targeting cancer-related inflammation.针对癌症相关炎症的药物的初步结果。
J Natl Cancer Inst. 2009 Aug 19;101(16):1110-2. doi: 10.1093/jnci/djp266. Epub 2009 Aug 11.
3
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer.基质小窝蛋白-1水平可预测导管原位癌早期进展为浸润性乳腺癌。
Cancer Biol Ther. 2009 Jun;8(11):1071-9. doi: 10.4161/cbt.8.11.8874. Epub 2009 Jun 29.
4
Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer.雌激素受体、孕激素受体及人表皮生长因子受体2（Her-2/neu）状态随时间的变化：原发性与转移性乳腺癌之间的不一致率
Anticancer Res. 2009 May;29(5):1557-62.
5
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin.用成纤维细胞激活蛋白激活的原促糜蛋白酶原靶向肿瘤基质。
Mol Cancer Ther. 2009 May;8(5):1378-86. doi: 10.1158/1535-7163.MCT-08-1170. Epub 2009 May 5.
6
Stromal cell expression of caveolin-1 predicts outcome in breast cancer.小窝蛋白-1的基质细胞表达可预测乳腺癌的预后。
Am J Pathol. 2009 Jun;174(6):2035-43. doi: 10.2353/ajpath.2009.080924. Epub 2009 May 1.
7
An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.基质中窖蛋白-1表达缺失预示着人类乳腺癌早期肿瘤复发及不良临床结局。
Am J Pathol. 2009 Jun;174(6):2023-34. doi: 10.2353/ajpath.2009.080873. Epub 2009 May 1.
8
The metastatic niche: adapting the foreign soil.转移微环境：适应异质土壤
Nat Rev Cancer. 2009 Apr;9(4):285-93. doi: 10.1038/nrc2621.
9
Microenvironmental regulation of metastasis.转移的微环境调节
Nat Rev Cancer. 2009 Apr;9(4):239-52. doi: 10.1038/nrc2618. Epub 2008 Mar 12.
10
Stromal signature identifies basal breast cancers.基质特征可识别基底样乳腺癌。
Nat Med. 2009 Mar;15(3):237-8; author reply 238. doi: 10.1038/nm0309-237.