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结肠镜检查的适应证和人口统计学特征是否会影响完成率?一项大型全国数据库评估。

Do indication and demographics for colonoscopy affect completion? A large national database evaluation.

机构信息

Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.

出版信息

Eur J Gastroenterol Hepatol. 2010 May;22(5):620-7. doi: 10.1097/MEG.0b013e3283352cd6.

Abstract

BACKGROUND AND AIM

Indication for colonoscopy has not been examined as a predictor of colonoscopy completion. We hypothesized that colonoscopy conducted for colorectal cancer screening might have higher in completion rates than colonoscopy conducted for other indications.

METHODS

The study design was a retrospective cohort. Colonoscopies recorded within the Clinical Outcomes Research Initiative database conducted between 1 January 2002 and 30 June 2003 were analyzed. Indication included: average-risk screening; surveillance; nonspecific abdominal symptoms; bleeding symptoms; or family history of colorectal carcinoma. Demographic factors and indication for colonoscopy were evaluated for the outcome of incomplete colonoscopy using logistic regression analysis.

RESULTS

129 549 Colonoscopy procedures were analyzed. Average risk screening seemed to be protective for completion (relative risk: 0.69; 95% confidence interval: 0.63-0.75). Bleeding and nonspecific symptoms had higher risk of incomplete procedure compared to other indications. Males had higher completion rates compared to females (relative risk: 0.62; 95% confidence interval: 0.58-0.66). Community setting had higher completion rates compared to academic or Veteran's administration sites. Increasing age was associated with higher rate of incomplete colonoscopy.

CONCLUSION

Colonoscopy conducted for screening indication has comparable completion rates when compared with other indications. An overall completion rate of around 95% was noted in this study. This is the largest study to date verifying that completion rates are meeting recommended multisociety guidelines in the USA. Nonspecific abdominal symptoms in Caucasian population, female sex, advanced age, clinical setting, and ethnic groups African-American and Hispanic were found to have increased risk of incomplete procedure.

摘要

背景与目的

结肠镜检查的适应证并未被视为结肠镜检查完成的预测因素。我们假设,用于结直肠癌筛查的结肠镜检查的完成率可能高于用于其他适应证的结肠镜检查。

方法

研究设计为回顾性队列研究。分析了 2002 年 1 月 1 日至 2003 年 6 月 30 日期间在临床结果研究倡议数据库中进行的结肠镜检查。适应证包括:一般风险筛查;监测;非特异性腹部症状;出血症状;或结直肠癌家族史。使用逻辑回归分析评估人口统计学因素和结肠镜检查适应证与结肠镜检查不完整的结局。

结果

共分析了 129549 例结肠镜检查。一般风险筛查似乎对完成有保护作用(相对风险:0.69;95%置信区间:0.63-0.75)。与其他适应证相比,出血和非特异性症状的操作不完整风险更高。与女性相比,男性的完成率更高(相对风险:0.62;95%置信区间:0.58-0.66)。社区医疗机构的完成率高于学术或退伍军人管理局医疗机构。年龄的增加与结肠镜检查不完整的风险增加有关。

结论

与其他适应证相比,用于筛查适应证的结肠镜检查具有可比的完成率。本研究中观察到总体完成率约为 95%。这是迄今为止最大的一项研究,证实了美国完成率符合多学会推荐的指南。在白种人群中,非特异性腹部症状、女性、高龄、临床环境以及非裔美国人和西班牙裔人群被发现操作不完整的风险增加。

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