计算分析确定人腺病毒 55 型为新出现的急性呼吸道疾病病原体。
Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen.
机构信息
Department of Bioinformatics and Computational Biology, George Mason University, 10900 University Blvd., MSN 5B3, Manassas, Virginia 20110, USA.
出版信息
J Clin Microbiol. 2010 Mar;48(3):991-3. doi: 10.1128/JCM.01694-09. Epub 2009 Dec 30.
Abstract
Novel human adenoviruses (HAdVs) arise from genome recombination. Analysis of HAdV type 55 from an outbreak in China shows a hexon recombination between HAdV-B11 and HAdV-B14, resulting in a genome that is 97.4% HAdV-B14. Sporadic appearances as a re-emergent pathogen and misidentification as "HAdV-B11a" are due to this partial hexon.
摘要
新型人类腺病毒（HAdV）来源于基因组重组。对中国爆发疫情中的 HAdV 型 55 的分析表明，HAdV-B11 和 HAdV-B14 之间存在六邻体重组，导致基因组 97.4%为 HAdV-B14。作为一种重新出现的病原体的偶发出现以及被错误鉴定为“ HAdV-B11a”，是由于这种部分六邻体。
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