Polisher Research Institute, Madlyn and Leonard Abramson Center for Jewish Life, 1425 Horsham Rd., North Wales, PA 19454-1320, USA.
Behav Sleep Med. 2010;8(1):48-61. doi: 10.1080/15402000903425769.
In this study, restless legs syndrome (RLS) risk factors, RLS-associated behaviors, and the ability to understand and answer an RLS diagnostic interview were investigated. In 23 older adults with early to moderate dementia and nighttime sleep disturbance, the most common risk factors for RLS were a periodic leg movement sleep index > 15 (54.55%), based on polysomnography, and use of selective serotonin reuptake inhibitors (SSRIs) (34.78%). The most common RLS-associated behaviors were repetitious mannerisms (56.52%) and general restlessness (34.78%), according to direct observation from research assistants. Finally, older adults with early to moderate dementia were unable to understand and reliably answer the RLS diagnostic interview. Older persons with mild to moderate dementia and sleep disturbance may require objective diagnostics to identify RLS.
本研究调查了不安腿综合征（RLS）的风险因素、与 RLS 相关的行为，以及理解和回答 RLS 诊断访谈的能力。在 23 名有夜间睡眠障碍的早期至中度痴呆老年人中，最常见的 RLS 风险因素是多导睡眠图检查的周期性腿部运动睡眠指数>15（54.55%），以及使用选择性 5-羟色胺再摄取抑制剂（SSRIs）（34.78%）。根据研究助理的直接观察，最常见的与 RLS 相关的行为是重复的怪癖（56.52%）和一般性躁动（34.78%）。最后，早期至中度痴呆的老年人无法理解和可靠地回答 RLS 诊断访谈。有轻度至中度痴呆和睡眠障碍的老年人可能需要进行客观诊断以确定 RLS。
