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使用老年行为检查表对精神病理学和适应功能进行广泛评估:验证和诊断鉴别研究。

Broad spectrum assessment of psychopathology and adaptive functioning with the Older Adult Behavior Checklist: a validation and diagnostic discrimination study.

机构信息

Duke University Medical Center, Durham, NC, USA.

出版信息

Int J Geriatr Psychiatry. 2010 Nov;25(11):1177-85. doi: 10.1002/gps.2459.

DOI:10.1002/gps.2459
PMID:20054835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2957545/
Abstract

OBJECTIVE

Self-administered by spouses and other collateral informants, the nationally normed Older Adult Behavior Checklist (OABCL) provides standardized data on diverse aspects of older adult psychopathology and adaptive functioning. We tested the validity of the Older Adult Behavior Checklist (OABCL) scale scores in terms of associations with diagnoses of dementia of the Alzheimer's type (DAT) and mood disorders (MD) and with nine measures of psychopathology, cognitive performance, and adaptive functioning.

METHOD

Informants completed OABCLs for 727 60-97-year-olds recruited from a memory disorders clinic, geriatric psychiatry clinic, and community-dwelling seniors. OABCL scale scores were tested for associations with DAT and MD diagnoses, as well as with scores on the Neuropsychiatric Inventory, Mini-Mental State Exam (MMSE), Clock Drawing Test, Alzheimer's Disease Assessment Scale, Geriatric Depression Scale, Clinical Dementia Rating, Dementia Severity Rating Scale, Trail Making Test Part A, and Instrumental Activities of Daily Living.

RESULTS

OABCL scales had medium to large correlations with the nine other indices of functioning and significantly augmented MMSE discrimination between patients with DAT versus MD. OABCL scales also discriminated significantly between patients diagnosed with DAT versus MD and both these groups versus nonclinical subjects.

CONCLUSIONS

Multiple OABCL scales had medium to large associations with diverse indices of functioning based on other kinds of data. The nationally normed OABCL provides new ways to integrate informant and self-report data to improve assessment of older adults. Specifically, the OABCL can provide discrimination between those who qualify for diagnoses of DAT versus MD versus neither diagnosis.

摘要

目的

由配偶和其他间接知情者自行填写的全国标准化老年行为检查表(OABCL)提供了关于老年精神病理学和适应功能的多个方面的标准化数据。我们根据与阿尔茨海默病型痴呆(DAT)和心境障碍(MD)的诊断以及与九项精神病理学、认知表现和适应功能的测量结果的相关性,检验了老年行为检查表(OABCL)量表评分的有效性。

方法

从记忆障碍诊所、老年精神病学诊所和社区居住的老年人中招募了 727 名 60-97 岁的参与者,其间接知情者填写了 OABCL。测试了 OABCL 量表评分与 DAT 和 MD 诊断的相关性,以及与神经精神病学检查、简易精神状态检查(MMSE)、时钟绘制测试、阿尔茨海默病评估量表、老年抑郁量表、临床痴呆评定量表、痴呆严重程度评定量表、连线测试 A 部分和日常生活活动工具的评分的相关性。

结果

OABCL 量表与其他九项功能指标具有中等至较大的相关性,并显著提高了 MMSE 对 DAT 与 MD 患者的区分度。OABCL 量表还能显著区分 DAT 与 MD 患者与这两组患者与非临床受试者。

结论

多个 OABCL 量表与基于其他类型数据的各种功能指标具有中等至较大的关联。全国标准化的 OABCL 提供了将知情者和自我报告数据整合以改善对老年人评估的新方法。具体而言,OABCL 可以在那些符合 DAT 与 MD 诊断标准的人与既不符合 DAT 也不符合 MD 诊断标准的人之间进行区分。

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