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BD GeneOhm MRSA 检测法对不同临床标本中耐甲氧西林金黄色葡萄球菌(MRSA)的快速检测与培养法的比较

Rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) in diverse clinical specimens by the BD GeneOhm MRSA assay and comparison with culture.

机构信息

Department of Medical Microbiology, Center for Laboratory Medicine, Luzerner Kantonsspital Luzern, 6000 Lucerne 16, Switzerland.

出版信息

J Clin Microbiol. 2010 Mar;48(3):981-4. doi: 10.1128/JCM.01990-09. Epub 2010 Jan 13.

Abstract

The efficacy of the BD GeneOhm methicillin-resistant Staphylococcus aureus (MRSA) assay was assessed by analyzing nasal swabs and swabs from other body sites for the presence of MRSA in a low-prevalence area. From 681 patients with a high risk for MRSA carriage, 1,601 specimens were collected and transported in Amies agar. After discordant analysis, the sensitivity, specificity, positive predictive value, and negative predictive value of the BD GeneOhm MRSA assay were 84.3%, 99.2%, 88.4%, and 98.9%, respectively, compared to culture.

摘要

BD GeneOhm 耐甲氧西林金黄色葡萄球菌 (MRSA) 检测的功效通过分析低流行地区鼻腔拭子和其他身体部位拭子中 MRSA 的存在来评估。从 681 名具有高耐甲氧西林金黄色葡萄球菌携带风险的患者中,共采集了 1601 份标本,并在 Amies 琼脂中运输。经不一致性分析,BD GeneOhm MRSA 检测与培养相比,其灵敏度、特异性、阳性预测值和阴性预测值分别为 84.3%、99.2%、88.4%和 98.9%。

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