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[不同照射剂量的氧化氚长期作用后体液免疫的恢复情况]

[The recovery of humoral immunity after the long-term action of tritium oxide at different irradiation levels].

作者信息

Smirnov D G, Okatenko M A

出版信息

Radiobiologiia. 1991 Jan-Feb;31(1):82-6.

PMID:2008528
Abstract

Dynamics of recovery of humoral immunity of CBA mice was studied 1, 3, 6 and 12 months after termination of long-term exposure to tritium oxide at various levels of absorbed doses (3, 5 and 9 Gy) and dose rates (3.3, 4.9 and 9.2 cGy.day-1). A severer and more stable residual radiation damage was observed in the department of lymphocyte precursors. A considerable decrease in the content of antibody producers was due to the lymphoid tissue hypoplasia. There was a direct relationship between the immunodeficiency and dose rate and total absorbed dose of beta radiation.

摘要

研究了CBA小鼠在不同吸收剂量(3、5和9 Gy)和剂量率(3.3、4.9和9.2 cGy·天⁻¹)下长期暴露于氧化氚终止后1、3、6和12个月时体液免疫的恢复动态。在淋巴细胞前体部位观察到更严重和更稳定的残余辐射损伤。抗体产生细胞数量的显著减少是由于淋巴组织发育不全。免疫缺陷与β辐射的剂量率和总吸收剂量之间存在直接关系。

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