Kirillova E N, Sokhranich A L
Radiobiologiia. 1989 Jul-Aug;29(4):511-4.
In experiments with Wistar rats a study was made of the content of antibody-forming cells (AFC) in the spleen at remote times (3 to 12 months) after intravenous injection of 239Pu(IV) in doses of 166, 55, and 18 kBq/kg body mass. The doses absorbed in the central and peripheral immunity organs were defined. Pronounced spleen hypoplasia and profound inhibition of humoral immunity were displayed 1 year after the injection of a small amount of the radionuclide. AFC deficiency in animals was amounted to 11-32 per cent throughout the entire period of observation.
在对Wistar大鼠进行的实验中，研究了在静脉注射剂量为166、55和18 kBq/kg体重的239Pu(IV)后，在3至12个月的远期，脾脏中抗体形成细胞（AFC）的含量。确定了中央和外周免疫器官中吸收的剂量。注射少量放射性核素1年后，出现明显的脾脏发育不全和体液免疫的深度抑制。在整个观察期内，动物体内AFC缺乏率达11%至32%。
