Kirillova E N, Nifatov A P, Revina V S
Radiobiologiia. 1990 Mar-Apr;30(2):179-84.
In experiments with CBA mice it was shown that the long-term influence of tritium oxide administered with drinking water daily during 180 days (370 kBq.g-1 of body mass, cumulative dose 8.7 Gy, dose rate 4.5 cGy.day-1) causes the development of immunity deficiency 90 days after the onset of the administration that persists for up to 270 days. There is a 34% decrease in the average life of irradiated animals and an increase in the number of malignant neoplasms (postmortem examination was performed after natural death or killing on days 250, 350 and 450). There is a direct relationship between the occurrence of malignant neoplasms and the immunity deficiency.
在对CBA小鼠进行的实验中发现，以每日通过饮用水给予氧化氚的方式进行为期180天的长期影响（体重370 kBq·g-1，累积剂量8.7 Gy，剂量率4.5 cGy·天-1），会在给药开始90天后导致免疫缺陷的出现，这种免疫缺陷会持续长达270天。受辐照动物的平均寿命缩短34%，恶性肿瘤数量增加（在自然死亡或于第250、350和450天处死动物后进行尸检）。恶性肿瘤的发生与免疫缺陷之间存在直接关联。
