Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
Cell. 2010 Jan 8;140(1):13-8. doi: 10.1016/j.cell.2009.12.034.
The induction of a protracted response to a brief stimulus is a form of cellular memory. Here we describe the role of transcriptional regulation in both natural and synthetic memory networks and discuss the potential applications of engineered memory networks in medicine and industrial biotechnology.
短暂刺激诱导长期反应是细胞记忆的一种形式。本文描述了转录调控在天然和人工记忆网络中的作用,并讨论了工程化记忆网络在医学和工业生物技术中的潜在应用。