Hauffe Heidi C, Niklasson Bo, Olsson Therese, Bianchi Alessandro, Rizzoli Annapaola, Klitz William
Environment and Natural Resources Area, IASMA Research and Innovation Centre, Fondazione E Mach, Via E Mach 1, S Michele all'Adige, Italy.
J Wildl Dis. 2010 Jan;46(1):262-6. doi: 10.7589/0090-3558-46.1.262.
Identified in 1998, Ljungan virus (LV; Picornaviridae) causes type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus) from Sweden and Denmark, and may be a zoonotic agent of several important diseases (e.g., intrauterine fetal death, type 1 diabetes, Guillain-Barré syndrome, and myocarditis). Using a real-time reverse transcriptase-polymerase chain reaction assay and sequence analysis, we detected LV in bank voles, and for the first time, in yellow-necked mice (Apodemus flavicollis) collected during 2006 from a site in northern Italy. The global distribution of LV and its role as a mammalian pathogen deserve further attention.
1998年被发现的吕永病毒（LV；微小核糖核酸病毒科）在来自瑞典和丹麦的棕背鼠平（黄毛鼠平）中引发1型糖尿病样症状和心肌炎，并且可能是几种重要疾病（例如，宫内胎儿死亡、1型糖尿病、吉兰-巴雷综合征和心肌炎）的人畜共患病原体。通过实时逆转录聚合酶链反应检测和序列分析，我们在棕背鼠平中检测到了LV，并且首次在2006年从意大利北部一个地点采集的黄颈鼠（黄颈姬鼠）中检测到了LV。LV的全球分布及其作为哺乳动物病原体的作用值得进一步关注。
