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在来自意大利北部的普通田鼠(黄毛鼠)和黄颈姬鼠中检测到伦贾病毒。

Ljungan virus detected in bank voles (Myodes glareolus) and yellow-necked mice (Apodemus flavicollis) from Northern Italy.

作者信息

Hauffe Heidi C, Niklasson Bo, Olsson Therese, Bianchi Alessandro, Rizzoli Annapaola, Klitz William

机构信息

Environment and Natural Resources Area, IASMA Research and Innovation Centre, Fondazione E Mach, Via E Mach 1, S Michele all'Adige, Italy.

出版信息

J Wildl Dis. 2010 Jan;46(1):262-6. doi: 10.7589/0090-3558-46.1.262.

Abstract

Identified in 1998, Ljungan virus (LV; Picornaviridae) causes type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus) from Sweden and Denmark, and may be a zoonotic agent of several important diseases (e.g., intrauterine fetal death, type 1 diabetes, Guillain-Barré syndrome, and myocarditis). Using a real-time reverse transcriptase-polymerase chain reaction assay and sequence analysis, we detected LV in bank voles, and for the first time, in yellow-necked mice (Apodemus flavicollis) collected during 2006 from a site in northern Italy. The global distribution of LV and its role as a mammalian pathogen deserve further attention.

摘要

1998年被发现的吕永病毒(LV;微小核糖核酸病毒科)在来自瑞典和丹麦的棕背鼠平(黄毛鼠平)中引发1型糖尿病样症状和心肌炎,并且可能是几种重要疾病(例如,宫内胎儿死亡、1型糖尿病、吉兰-巴雷综合征和心肌炎)的人畜共患病原体。通过实时逆转录聚合酶链反应检测和序列分析,我们在棕背鼠平中检测到了LV,并且首次在2006年从意大利北部一个地点采集的黄颈鼠(黄颈姬鼠)中检测到了LV。LV的全球分布及其作为哺乳动物病原体的作用值得进一步关注。

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