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在穿孔性憩室炎急诊剖腹手术决策过程中使用严重程度分类系统。

Use of severity classification systems in the surgical decision-making process in emergency laparotomy for perforated diverticulitis.

机构信息

Department of Surgery, Triemli Hospital, 8063 Zurich, Switzerland.

出版信息

Int J Colorectal Dis. 2010 Apr;25(4):463-70. doi: 10.1007/s00384-009-0852-6. Epub 2009 Nov 29.

Abstract

PURPOSE

Hartman's procedure (HP) or primary anastomosis (PA) are the two surgical techniques used in patients undergoing emergency colectomy for perforated diverticulitis. There are no objective criteria to guide the surgeon's choice of procedure. This study assesses whether classification and scoring systems can be used in the decision-making process.

METHODS

One hundred eleven patients undergoing emergency laparotomy for perforated diverticulitis were analyzed. Logistic regression and interaction models were used to determine the predictive value in the two settings.

RESULTS

Sixty five patients underwent HP and 46 patients underwent PA. Patients with HP had significantly higher scores, median age, and were more often on immunosuppressive medication. Mortality and surgical morbidity did not differ between the groups. The clinical anastomotic leak rate was 28.3% in the PA group. In the univariate logistic regression for in-hospital death, all scores showed a significant influence. The multivariate logistic regression analysis showed that only Charlson comorbidity index (CCI) and American Society of Anesthesiologists score had a significant influence on mortality. Each score was analyzed for its predictive value regarding mortality and morbidity with respect to type of operative procedure. Only CCI revealed a trend towards statistical significance. The risk of death increases with increasing CCI when PA is performed compared to HP.

CONCLUSION

None of the tested scores can be used to help the surgeon decide whether a PA or HP is appropriate in a specific patient. Comorbidity, represented as CCI in this study, might be more important than the locoregional situation.

摘要

目的

Hartman 手术(HP)或一期吻合术(PA)是用于因穿孔性憩室炎而行急诊结肠切除术的两种手术技术。目前尚无客观标准来指导外科医生选择手术方法。本研究评估分类和评分系统是否可用于决策过程。

方法

分析了 111 例行急诊剖腹手术治疗穿孔性憩室炎的患者。使用逻辑回归和交互模型在两种情况下确定预测值。

结果

65 例患者行 HP,46 例行 PA。HP 组患者的评分、中位年龄显著更高,且更常接受免疫抑制药物治疗。两组的死亡率和手术发病率无差异。PA 组临床吻合口漏的发生率为 28.3%。在单变量逻辑回归分析中,所有评分均对院内死亡有显著影响。多变量逻辑回归分析显示,只有 Charlson 合并症指数(CCI)和美国麻醉医师协会评分对死亡率有显著影响。每个评分均针对死亡率和发病率进行分析,以了解手术类型的影响。只有 CCI 显示出统计学意义的趋势。与 HP 相比,当行 PA 时,CCI 越高,死亡风险越高。

结论

在特定患者中,没有任何一种测试评分可用于帮助外科医生决定行 PA 还是 HP。在本研究中,代表合并症的 CCI 可能比局部区域情况更重要。

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