The Department of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA.
AIDS Behav. 2011 Oct;15(7):1475-82. doi: 10.1007/s10461-010-9667-2.
Little is known about how the structure of work affects adherence to HIV antiretroviral therapy. We surveyed participants in an adherence intervention study to learn more about job characteristics, including measures of psychological demand and control, and job accommodations. Adherence was assessed using the Medication Event Monitoring System. Of 156 trial subjects, 69 were employed, and these 69 made 229 study visits. Psychological demands and control were unrelated to adherence, but the presence of workplace accommodations was significantly associated with adherence (P < 0.05). In multivariable models adjusting for clustering, those who reported having received an accommodation were 12% more adherent than those who did not receive an accommodation. Adherence was unrelated to experiencing side effects affecting work performance. Having the ability to institute job accommodations was more important to adherence than the psychosocial structure of the work. These potential benefits of requesting modifications need to be weighed against the possible risks of workplace disclosure.
关于工作结构如何影响 HIV 抗逆转录病毒治疗的依从性，我们知之甚少。我们调查了参与依从性干预研究的参与者，以了解更多关于工作特征的信息，包括心理需求和控制的措施，以及工作调整。依从性通过用药事件监测系统进行评估。在 156 名试验受试者中，有 69 人就业，这些人进行了 229 次研究访问。心理需求和控制与依从性无关，但工作场所调整的存在与依从性显著相关（P < 0.05）。在调整聚类的多变量模型中，报告接受调整的人比未接受调整的人依从性高 12%。依从性与影响工作表现的副作用无关。有能力进行工作调整对依从性更为重要，而不是工作的心理社会结构。需要权衡请求修改可能带来的潜在益处与工作场所披露的可能风险。
