Lu Minyi, Safren Steven A, Skolnik Paul R, Rogers William H, Coady William, Hardy Helene, Wilson Ira B
Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, #345, 750 Washington St., Boston, MA 02111, USA.
AIDS Behav. 2008 Jan;12(1):86-94. doi: 10.1007/s10461-007-9261-4. Epub 2007 Jun 19.
Self-reported measures of antiretroviral adherence vary greatly in recall time periods and response tasks. To determine which time frame is most accurate, we compared 3-, 7-day, and 1-month self-reports with data from medication event monitoring system (MEMS). To determine which response task is most accurate we compared three different 1-month self-report tasks (frequency, percent, and rating) to MEMS. We analyzed 643 study visits made by 156 participants. Over-reporting (self-report minus MEMS) was significantly less for the 1-month recall period (9%) than for the 3 (17%) or 7-day (14%) periods. Over-reporting was significantly less for the 1-month rating task (3%) than for the 1-month frequency and percent tasks (both 12%). We conclude that 1-month recall periods may be more accurate than 3- or 7-day periods, and that items that ask respondents to rate their adherence may be more accurate than those that ask about frequencies or percents.
自我报告的抗逆转录病毒治疗依从性测量在回忆时间段和回答任务方面差异很大。为了确定哪个时间框架最准确，我们将3天、7天和1个月的自我报告与用药事件监测系统（MEMS）的数据进行了比较。为了确定哪种回答任务最准确，我们将三种不同的1个月自我报告任务（频率、百分比和评分）与MEMS进行了比较。我们分析了156名参与者的643次研究访问。1个月回忆期的过度报告（自我报告减去MEMS）（9%）明显低于3天（17%）或7天（14%）的回忆期。1个月评分任务的过度报告（3%）明显低于1个月频率和百分比任务（均为12%）。我们得出结论，1个月的回忆期可能比3天或7天的回忆期更准确，并且要求受访者对其依从性进行评分的项目可能比询问频率或百分比的项目更准确。
