Epidemiology Research Center, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA.
Am J Obstet Gynecol. 2010 Apr;202(4):373.e1-9. doi: 10.1016/j.ajog.2009.11.029. Epub 2010 Jan 22.
The purpose of this study was to measure the occurrence and natural history of simple ovarian cysts in a cohort of older women.
Simple cysts were ascertained among a cohort of 15,735 women from the intervention arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial through 4 years of transvaginal ultrasound screening.
Simple cysts were seen in 14% of women the first time that their ovaries were visualized. The 1-year incidence of new simple cysts was 8%. Among ovaries with 1 simple cyst at the first screen, 54% retained 1 simple cyst, and 32% had no cyst 1 year later. Simple cysts did not increase risk of subsequent invasive ovarian cancer.
Simple ovarian cysts are fairly common among postmenopausal women, and most cysts appear stable or resolve by the next annual examination. These findings support recent recommendations to follow unilocular simple cysts in postmenopausal women without intervention.
本研究旨在测量在一组老年女性中单纯性卵巢囊肿的发生和自然史。
通过对前列腺癌、肺癌、结直肠癌和卵巢癌筛查试验干预组的 15735 名女性进行 4 年的经阴道超声筛查，确定单纯性囊肿。
在首次观察到卵巢的女性中，14%的女性存在单纯性囊肿。新的单纯性囊肿的 1 年发病率为 8%。在首次筛查时存在 1 个单纯性囊肿的卵巢中，54%保留了 1 个单纯性囊肿，32%在 1 年后没有囊肿。单纯性囊肿不会增加后续侵袭性卵巢癌的风险。
绝经后妇女中单纯性卵巢囊肿相当常见，大多数囊肿在次年检查时稳定或消失。这些发现支持最近的建议，即对绝经后妇女中的单房单纯性囊肿进行随访，而无需干预。
