Ghazi H A, Spielberger C, Källén B
Department of Embryology, University of Lund, Sweden.
Fertil Steril. 1991 Apr;55(4):726-32. doi: 10.1016/s0015-0282(16)54238-1.
Among a total of 379,779 women with 383,589 infants born in Sweden (1983 to 1986), 7.8% had a recorded period of infertility of at least 1 year. Women with a history of infertility had a higher mean age, a lower parity, had fewer previous induced abortions but more spontaneous abortions, extrauterine pregnancies, and stillbirths than women without a history of infertility. They also smoked more. There was an excess of multiple births. Singleton infants showed an increased percentage of low-birth weight infants, short gestational duration, and signs of intrauterine growth retardation. The rate of major malformations was not increased in the total infertile group but may have been increased in the subgroup with at least 4 years of infertility.
在瑞典1983年至1986年出生的383,589名婴儿的379,779名女性中,7.8%的女性有至少1年的不孕记录。有不孕史的女性平均年龄较高,生育次数较少,既往人工流产较少,但自然流产、宫外孕和死产比无不孕史的女性更多。她们吸烟也更多。多胞胎数量过多。单胎婴儿中低体重婴儿、孕期短和宫内生长迟缓迹象的比例增加。不孕组总体的严重畸形率没有增加,但不孕至少4年的亚组中可能有所增加。