一项非对照开放性试点研究，旨在评估饮食排除法在减轻婴幼儿特应性皮炎严重程度方面的作用。
An uncontrolled open pilot study to assess the role of dietary eliminations in reducing the severity of atopic dermatitis in infants and children.
作者信息
Dhar Sandipan, Malakar Rajib, Banerjee Raghubir, Chakraborty Saswati, Chakraborty Jayanti, Mukherjee Susmita
机构信息
Department of Pediatric Dermatology Kolkata, India.
出版信息
Indian J Dermatol. 2009;54(2):183-5. doi: 10.4103/0019-5154.53187.
BACKGROUND
The severity of atopic dermatitis (AD) has been reported to be reduced by dietary eliminations in a subset of patients with AD.
AIMS
To assess the reduction of the severity of atopic dermatitis in infants and children after eliminations of certain dietary items.
MATERIALS AND METHODS
The study group comprised of 100 children with atopic dermatitis. Their severity of itching, surface area of involvement, and SCORAD index were measured. Patients who did not have any systemic disease or were not on systemic corticosteroids were included in the study. Selected patients were advised to strictly adhere to a diet excluding milk and milk products, all kinds of nuts and nut-containing foods, egg and egg-containing foods, seafish and prawns, brinjal and soyabean for a period of 3 weeks. Instead of these avoided items, the food items to be included freely to maintain proper nutrition were dal and dal products, rohu fish, chicken, and fruits. All the preintervention parameters were measured again after 3 weeks.
RESULTS
There was a statistically significant reduction in severity scores after dietary elimination alone.
CONCLUSION
Dietary elimination helped to alleviate symptoms and signs in a subset of infants and children with AD.
背景
据报道，部分特应性皮炎（AD）患者通过饮食排除法，其病情严重程度有所减轻。
目的
评估排除某些饮食项目后，婴幼儿及儿童特应性皮炎严重程度的降低情况。
材料与方法
研究组由100名特应性皮炎患儿组成。测量他们的瘙痒严重程度、受累表面积及SCORAD指数。研究纳入无任何全身性疾病或未使用全身性皮质类固醇的患者。建议选定的患者严格坚持一种饮食方案，即3周内排除牛奶及奶制品、各类坚果及含坚果的食物、鸡蛋及含鸡蛋的食物、海鱼和虾、茄子和大豆。作为这些应避免食物的替代，可自由食用以维持适当营养的食物包括豆类及豆制品、鲃鱼、鸡肉和水果。3周后再次测量所有干预前的参数。
结果
仅通过饮食排除，严重程度评分就有统计学意义的降低。
结论
饮食排除有助于减轻部分婴幼儿及儿童AD患者的症状和体征。
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