低敏饮食会影响特应性皮炎的严重程度。
Hypoallergenic diet can influence the severity of atopic dermatitis.
作者信息
Celakovská Jarmila, Bukač Josef
机构信息
Department of Dermatology and Venereology, Faculty Hospital, Hradec Králové, Czech Republic.
出版信息
Indian J Dermatol. 2013 May;58(3):239. doi: 10.4103/0019-5154.110839.
AIM
To evaluate with SCORAD system the contribution of the diagnostic hypoallergenic diet on the severity of atopic dermatitis and especially on the the intensity criteria and subjective parametersin patients over 14 years of age.
MATERIALS AND METHODS
The diagnostichypoallergenic diet was recommended for the period of 3 weeks. Severity of eczema was scored in agreement with SCORAD score, and especially the intensity criteria (erythema, edema, crusting, excoriations, lichenifications, dryness) and subjective parameters (pruritus, sleeplessness) were evaluated at the beginning and at the end of this diet.
RESULTS
One hundred and forty-eight patients suffering from atopic dermatitis were included in the study: 107 women and 41 men with the average age of 26.03 (s.d. 9.6 years), min. 14 max. 63 years. In the end of 3 weeks diagnostic hypoallergenic diet there was a statistically significant reduction in severity of sleepless and pruritus and in all of the intensity criteria except of lichenification.
CONCLUSION
The diagnostic hypoallergenic diet can improve the intensity criteria and subjective parameters of atopic dermatitis evaluated in SCORAD, but not the lichenification. We recommend to introduce this diet before a challenge tests and as a temporary medical arrangement in patients suffering from moderate or severe form of atopic dermatitis.
目的
使用SCORAD系统评估诊断性低敏饮食对14岁以上特应性皮炎严重程度的影响，尤其是对强度标准和主观参数的影响。
材料与方法
建议进行为期3周的诊断性低敏饮食。根据SCORAD评分对湿疹严重程度进行评分，尤其在饮食开始和结束时评估强度标准（红斑、水肿、结痂、抓痕、苔藓化、干燥）和主观参数（瘙痒、失眠）。
结果
148例特应性皮炎患者纳入研究：107名女性和41名男性，平均年龄26.03岁（标准差9.6岁），最小14岁，最大63岁。在3周诊断性低敏饮食结束时，失眠和瘙痒的严重程度以及除苔藓化外的所有强度标准均有统计学显著降低。
结论
诊断性低敏饮食可改善SCORAD评估的特应性皮炎的强度标准和主观参数，但不能改善苔藓化。我们建议在激发试验前引入这种饮食，并作为中度或重度特应性皮炎患者的临时医疗安排。
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