The importance of anniversaries.

This year marks a number of important anniversaries for the Three Rs and those organisations involved in their advancement. These include the 50th anniversary of the publication of Russell and Burch's book, The Principles of Humane Experimental Technique, the 40th anniversary of FRAME, and the 5th anniversary for the UK's National Centre for the 3Rs. These anniversaries provide an important opportunity to reflect on past achievements and future challenges.