Veterinary Sciences, School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland.
Epidemiol Infect. 2010 May;138(5):764-71. doi: 10.1017/S0950268809991580. Epub 2010 Jan 29.
This study involved the phenotypic and molecular characterization of a population of methicillin-resistant Staphylococcus aureus isolates from animals and from veterinary personnel in Ireland. Isolates from 77 animals (dogs, n=44; cats, n=4; horses, n=29) and from 28 veterinary personnel were characterized using their antimicrobial resistance profiles and pulsed-field gel electrophoresis patterns. In addition, a representative number of these isolates (n=52) were further analysed using spa-typing techniques. The results obtained identified the presence of three distinct clonal complexes, CC5, CC8 and CC22, in both animal and human isolates. Two of these clonal complexes, CC8 and CC22, respectively, have been previously described in animals in Ireland but the presence of the third complex CC5 is a novel finding. The significance of this development, in relation to human and animal healthcare, is discussed.
本研究对来自爱尔兰动物和兽医人员的耐甲氧西林金黄色葡萄球菌分离株进行了表型和分子特征分析。从 77 只动物（狗，n=44；猫，n=4；马，n=29）和 28 名兽医人员中分离出的分离株，通过其抗菌药物耐药谱和脉冲场凝胶电泳图谱进行了特征分析。此外，对这些分离株中的一部分（n=52）使用 spa 分型技术进一步进行了分析。结果确定了三个不同的克隆复合体 CC5、CC8 和 CC22 存在于动物和人类分离株中。这两个克隆复合体，CC8 和 CC22，分别在爱尔兰的动物中已有报道，但第三个克隆复合体 CC5 的存在是一个新发现。讨论了这种发展与人类和动物保健的关系。
