深入了解分子埃立克体与宿主的相互作用。
New insights into molecular Ehrlichia chaffeensis-host interactions.
机构信息
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.
出版信息
Microbes Infect. 2010 May;12(5):337-45. doi: 10.1016/j.micinf.2010.01.009. Epub 2010 Jan 29.
Abstract
Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and survives by reprogramming the host cell. Here we review new information regarding the newly characterized effector molecules and the complex network of molecular host-pathogen interactions that the organism exploits enabling it to thrive and persist intracellularly.
摘要
查菲埃立克体是一种严格的细胞内细菌，对单核吞噬细胞具有趋化性，并通过重编程宿主细胞而存活。在这里，我们回顾了新的关于新特征的效应分子的信息，以及该生物利用的复杂的分子宿主-病原体相互作用网络，使它能够在细胞内茁壮成长和持续存在。
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