Cognitive Neurology and Alzheimer's Disease Center, Northwestern University Feinberg School of Medicine, 320 East SuperiorStreet,Chicago, IL 60611, USA.
Am J Alzheimers Dis Other Demen. 2010 Mar;25(2):125-7. doi: 10.1177/1533317509356691. Epub 2010 Feb 1.
Primary Progressive Aphasia (PPA) is a neurodegenerative disorder initially presenting with progressive language imapirment. This article provides a clinically oriented review of PPA. Different clinical presentations and imaging findings of 3 subtypes, agrammatic, semantic and logopenic, are presented. Underlying neuropathology, medical and social management aspects of these patients are reviewed.
原发性进行性失语症（PPA）是一种神经退行性疾病，最初表现为进行性语言障碍。本文对 PPA 进行了临床综述。介绍了 3 种亚型（语法性、语义性和完全性）的不同临床表现和影像学发现。还回顾了这些患者的神经病理学、医学和社会管理方面。
