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癌症患者中性粒细胞的功能异常:吞噬作用低效及反向内吞作用。

Functional abnormalities of neutrophils in cancer patients : inefficient phagocytosis and reverse endocytosis.

作者信息

Henon P, Gerota I, Palacios S

出版信息

Biomedicine. 1977 Oct;27(7):261-6.

PMID:201311
Abstract

A study of neutrophil functions has been performed in 17 patients with advanced cancer and in 21 controls. Their phagocytic activity, their index of reduction of NBT and their myeloperoxidase activity were examined. The reslts suggest that cancer patients might have a "factor" or "factors" in their plasma which interfereu (s) with phagocytosis and which promote (s) exocytosis of lysosomal enzymes ("reverse endocytosis") from from autologous polymorphonuclear leucocytes as well as from cells obtained from normal healthy donors.

摘要

对17例晚期癌症患者和21名对照者的中性粒细胞功能进行了研究。检测了他们的吞噬活性、NBT还原指数和髓过氧化物酶活性。结果表明,癌症患者血浆中可能存在一种或多种“因子”,这些因子会干扰吞噬作用,并促进自体多形核白细胞以及从正常健康供体获取的细胞中溶酶体酶的胞吐作用(“反向内吞作用”)。

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Functional abnormalities of neutrophils in cancer patients : inefficient phagocytosis and reverse endocytosis.癌症患者中性粒细胞的功能异常:吞噬作用低效及反向内吞作用。
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Function of polymorphonuclear neutrophilic leucocytes. Comparison of leucocytes from blood and exudate in healthy volunteers.多形核中性粒细胞的功能。健康志愿者血液与渗出液中白细胞的比较。
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