Farooqui B J, Khurshid M, Ashfaq M K, Khan M A
Department of Microbiology, The Aga Khan University Hospital, Karachi, Pakistan.
J Clin Pathol. 1991 Mar;44(3):258-9. doi: 10.1136/jcp.44.3.258.
Over three years, a comparative study on 100 selected patients with fever of unknown origin was undertaken to determine the yield of Salmonella typhi from their blood and bone marrow cultures. The results indicate that in patients who had an infection with S typhi the organism was isolated from the bone marrow in all of them and from the blood in only 66%. This suggests that bone marrow cultures may be attempted when blood cultures are negative for bacterial growth after three to four days of incubation.
在三年时间里,对100例选定的不明原因发热患者进行了一项比较研究,以确定从他们的血液和骨髓培养物中分离出伤寒沙门氏菌的阳性率。结果表明,在感染伤寒沙门氏菌的患者中,该菌在所有患者的骨髓中均可分离出来,而在血液中的分离率仅为66%。这表明,在血液培养物经过三到四天孵育后细菌生长呈阴性时,可尝试进行骨髓培养。