Gilman R H, Terminel M, Levine M M, Hernandez-Mendoza P, Hornick R B
Lancet. 1975 May 31;1(7918):1211-3. doi: 10.1016/s0140-6736(75)92194-7.
The recovery of Salmonella typhi from blood, rectal swab, urine, bone-marrow, and rose spots was compared in 62 patients with typhoid fever, most of whom had received some antibiotic therapy before presentation. S. typhi was isolated from culture of bone-marrow in 56 patients (90%); in contrast, S. typhi was recovered from blood in only 25 (40%), from stool in 23 (37%), and urine in 4 (7%). S. typhi was isolated from 24 (63%) of 38 patients who had rose-spot cultures. If culture sites had been limited to blood, stool, and urine, the bacteriological diagnosis would have been missed in 24 patients.
对62例伤寒热患者血液、直肠拭子、尿液、骨髓和玫瑰疹处的伤寒沙门氏菌检出情况进行了比较，其中大多数患者在就诊前已接受过某种抗生素治疗。56例患者（90%）的骨髓培养分离出伤寒沙门氏菌；相比之下，仅25例（40%）患者血液中检出伤寒沙门氏菌，23例（37%）患者粪便中检出，4例（7%）患者尿液中检出。38例进行玫瑰疹培养的患者中，24例（63%）分离出伤寒沙门氏菌。如果培养部位仅限于血液、粪便和尿液，24例患者的细菌学诊断将会漏诊。
