Department of Urology, KH Hietzing mit Neurologischem Zentrum Rosenhügel & Ludwig Boltzmann Institut für Andrologie und Urologie, Vienna, Austria.
Reprod Biol Endocrinol. 2010 Feb 5;8:12. doi: 10.1186/1477-7827-8-12.
To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations.
This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and motility according to seminal leukocytes (PMNL) concentration (category A: >0 to <0.25 x 10(6)/mL; category B: >0.25 to <0.5 x 10(6)/mL; category C: >0.5 to <0.75 x 10(6)/mL; category D: >0.75 to <1.0 x 10(6)/mL, category E: >1 x 10(6)/mL).
The percentage of sperm with normal morphology increased significantly from category A (14%) to category D (19%) but decreased in category E to levels (14%) similar to those in category A. Motility grades a and a+b (combined) also increased from category A (12%, 20%) to category D (18.0%, 28.5%) and decreased in category E (11%, 20.5%) to levels similar to those in category A. Sperm deformities and motility grades c and d increased progressively in all categories.
Leukocytes had a positive association with normal morphology and progressive motility in semen samples at a concentration of 0-1 x 10(6)/mL. The findings suggest that the association between leukocytes (PMNL) and semen quality might be concentration dependent.
评估不同白细胞浓度下白细胞（多形核粒细胞-PMNL）与精液参数的关系。
这是一项在大学医院男科诊所进行的回顾性临床研究。根据精液中白细胞（PMN）浓度（A 类：>0 至<0.25×10（6）/mL；B 类：>0.25 至<0.5×10（6）/mL；C 类：>0.5 至<0.75×10（6）/mL；D 类：>0.75 至<1.0×10（6）/mL；E 类：>1×10（6）/mL）分析不育男性的精子形态和活力。
正常形态精子的百分比从 A 类（14%）显著增加到 D 类（19%），但在 E 类中下降到与 A 类相似的水平（14%）。运动等级 a 和 a+b（合并）也从 A 类（12%，20%）增加到 D 类（18.0%，28.5%），在 E 类（11%，20.5%）中下降到与 A 类相似的水平。畸形精子和运动等级 c 和 d 在所有类别中都呈递增趋势。
白细胞与浓度在 0-1×10（6）/mL 之间的精液样本中的正常形态和渐进性运动呈正相关。研究结果表明，白细胞（PMN）与精液质量之间的关系可能与浓度有关。
