University of Michigan, School of Dentistry, Department of Cariology, Restorative Sciences and Endodontics, Room 2345, 1100 N. University, Ann Arbor, MI 48109, USA.
J Dent Res. 2010 Mar;89(3):286-91. doi: 10.1177/0022034509360155. Epub 2010 Feb 5.
Minimally invasive caries-removal procedures remove only caries-infected dentin and preserve caries-affected dentin that becomes remineralized. Dental cements containing calcium phosphate promote remineralization. This study evaluated the in vivo remineralization capacity of resin-based calcium-phosphate cement (Ca-P) used for indirect pulp-capping. Carious and sound teeth indicated for extraction were randomly restored with the Ca-P base or without base (control), followed by adhesive restoration. Study teeth were extracted after three months, followed by elemental analysis of the cavity floor. Mineral content of affected or sound dentin at the cavity floor was quantified by electron probe micro-analysis to 100-mum depth. After three months, caries-affected dentin underneath the Ca-P base showed significantly increased calcium and phosphorus content to a depth of 30 mum. Mineral content of treated caries-affected dentin was in the range of healthy dentin, revealing the capacity of Ca-P base to promote remineralization of caries-affected dentin.
微创龋齿去除程序仅去除受感染的牙本质并保留可再矿化的受龋齿影响的牙本质。含磷酸钙的牙科水泥促进再矿化。本研究评估了用于间接盖髓的树脂基磷酸钙水泥 (Ca-P) 的体内再矿化能力。为提取而指定的龋齿和健康牙齿被随机用 Ca-P 基底或无基底（对照）修复，然后进行粘合修复。三个月后提取研究牙齿，然后对腔底进行元素分析。通过电子探针微分析定量腔底受影响或健康牙本质的矿物质含量，深度为 100 微米。三个月后，Ca-P 基底下的受龋齿影响的牙本质在 30 微米深度处显示出钙和磷含量的显著增加。处理过的受龋齿影响的牙本质的矿物质含量处于健康牙本质的范围内，表明 Ca-P 基底有能力促进受龋齿影响的牙本质的再矿化。
