Vilela Handially, Nakamura Mariana, Braga Roberto
Department of Biomaterials and Oral Biology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Biomater Investig Dent. 2025 Aug 28;12:44586. doi: 10.2340/biid.v12.44586. eCollection 2025.
Ca release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO.2HO, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.
Specimens were individually immersed in deionized water ( = 3). Every 2 weeks, immersion medium was collected and specimens were transferred to new vials with fresh medium. Ca release was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha: 5%).
Ca release was observed during the entire 12-month period. Cumulative release was 1635.1 ± 145.3 μg/cm (179.7 ± 16.0 ppm), corresponding to 23.8 ± 2.0% of the total Ca mass in the specimen.
The tested composite was capable of sustained Ca release in water for 1 year. In spite of the limitations of this screening test, the results suggest that composites containing Calcium phosphate (CaP) particles could offer a long-term Ca supply to the adjacent dental tissues.
在1年的时间里，对含有二水磷酸二钙颗粒（CaHPO₄·2H₂O，二水磷酸二钙[DCPD]）的复合材料制成的标本中的钙释放情况进行了跟踪研究。
将标本分别浸入去离子水中（n = 3）。每2周收集一次浸泡介质，并将标本转移到装有新鲜介质的新小瓶中。使用电感耦合等离子体发射光谱法（ICP - OES）对钙释放进行定量分析。数据通过方差分析/ Tukey检验进行分析（α：5%）。
在整个12个月期间均观察到钙释放。累积释放量为1635.1±145.3μg/cm²（179.7±16.0ppm），相当于标本中总钙质量的23.8±2.0%。
所测试的复合材料能够在水中持续释放钙达1年。尽管该筛选试验存在局限性，但结果表明含有磷酸钙（CaP）颗粒的复合材料可为相邻的牙组织提供长期的钙供应。
