Section on Biological Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Semin Cell Dev Biol. 2010 Aug;21(6):616-21. doi: 10.1016/j.semcdb.2010.02.001. Epub 2010 Feb 6.
Newly emerging genetic studies have revealed that a subset of the family of glycosyltransferases responsible for the formation of mucin-type O glycans is essential for normal development. As additional genetic, biochemical and physical tools are developed to interrogate the complex structure and surface location of this under-studied class of carbohydrate, no doubt additional roles will be elucidated.
新出现的遗传研究表明，负责形成粘蛋白型 O 聚糖的糖基转移酶家族的一部分对于正常发育是必不可少的。随着更多的遗传、生化和物理工具被开发出来，以研究这一研究较少的碳水化合物类别复杂的结构和表面位置，毫无疑问，将会揭示更多的作用。
