黏蛋白型 O-聚糖在真核生物发育中的作用。
The role of mucin-type O-glycans in eukaryotic development.
机构信息
Section on Biological Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Semin Cell Dev Biol. 2010 Aug;21(6):616-21. doi: 10.1016/j.semcdb.2010.02.001. Epub 2010 Feb 6.
Abstract
Newly emerging genetic studies have revealed that a subset of the family of glycosyltransferases responsible for the formation of mucin-type O glycans is essential for normal development. As additional genetic, biochemical and physical tools are developed to interrogate the complex structure and surface location of this under-studied class of carbohydrate, no doubt additional roles will be elucidated.
摘要
新出现的遗传研究表明，负责形成粘蛋白型 O 聚糖的糖基转移酶家族的一部分对于正常发育是必不可少的。随着更多的遗传、生化和物理工具被开发出来，以研究这一研究较少的碳水化合物类别复杂的结构和表面位置，毫无疑问，将会揭示更多的作用。
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