Bioinformatics and Computational Biology Program, Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Plant Physiol. 2010 Apr;152(4):1807-16. doi: 10.1104/pp.109.151027. Epub 2010 Feb 10.
PlantMetabolomics.org (PM) is a web portal and database for exploring, visualizing, and downloading plant metabolomics data. Widespread public access to well-annotated metabolomics datasets is essential for establishing metabolomics as a functional genomics tool. PM integrates metabolomics data generated from different analytical platforms from multiple laboratories along with the key visualization tools such as ratio and error plots. Visualization tools can quickly show how one condition compares to another and which analytical platforms show the largest changes. The database tries to capture a complete annotation of the experiment metadata along with the metabolite abundance databased on the evolving Metabolomics Standards Initiative. PM can be used as a platform for deriving hypotheses by enabling metabolomic comparisons between genetically unique Arabidopsis (Arabidopsis thaliana) populations subjected to different environmental conditions. Each metabolite is linked to relevant experimental data and information from various annotation databases. The portal also provides detailed protocols and tutorials on conducting plant metabolomics experiments to promote metabolomics in the community. PM currently houses Arabidopsis metabolomics data generated by a consortium of laboratories utilizing metabolomics to help elucidate the functions of uncharacterized genes. PM is publicly available at http://www.plantmetabolomics.org.
PlantMetabolomics.org (PM) 是一个用于探索、可视化和下载植物代谢组学数据的网络门户和数据库。广泛向公众提供经过充分注释的代谢组学数据集对于将代谢组学确立为功能基因组学工具至关重要。PM 集成了来自多个实验室的不同分析平台生成的代谢组学数据,以及比率和误差图等关键可视化工具。可视化工具可以快速显示一个条件与另一个条件的比较情况,以及哪些分析平台显示出最大的变化。该数据库试图根据不断发展的代谢组学标准倡议,捕获实验元数据的完整注释以及基于代谢物丰度的数据库。PM 可以作为一个平台,通过在不同环境条件下对具有遗传独特性的拟南芥(Arabidopsis thaliana)群体进行代谢组学比较来得出假设。每个代谢物都与相关的实验数据和来自各种注释数据库的信息相关联。该门户还提供了关于进行植物代谢组学实验的详细协议和教程,以促进社区中的代谢组学发展。PM 目前位于 http://www.plantmetabolomics.org,其中包含了一个由利用代谢组学来帮助阐明未鉴定基因功能的实验室组成的联盟生成的拟南芥代谢组学数据。