Memory Disorders Research Group, Department of Neurology, University Hospital of Copenhagen Rigshospitalet, Copenhagen, Denmark.
Dement Geriatr Cogn Disord. 2010;29(2):146-53. doi: 10.1159/000269933. Epub 2010 Feb 11.
To study the trend of diagnosing dementia in the secondary health care sector over time, we conducted a nationwide longitudinal study of the incidence and prevalence of registered dementia diagnoses in the Danish national hospital registers.
All Danish residents born before 1964 and alive at their 40th birthday were followed from their 40th birthday or January 1, 1970, whichever came later, to the date of the first dementia diagnosis recorded in the hospital registers, the date of emigration, date of death, or December 31, 2004, whichever came first. The age- and period-specific incidence and prevalence of dementia were calculated and compared to estimates from large community-based cohort studies in Europe.
The study population consisted of 4,723,838 persons with 81,090,583 person-years of follow-up. 154,152 dementia cases were registered from 1970 to 2004. The incidence and prevalence of registered dementia diagnoses showed an increasing trend over time. In 2003, the age-standardized incidence rate ratio was 0.66 when compared to estimates from large European community-based cohort studies.
The study shows a marked improvement in the diagnostic rate of dementia in secondary care over time and indicates that this sector can be an important point of entry for patients with dementia.
为了研究二级保健部门诊断痴呆症的趋势随时间的变化，我们对丹麦国家医院登记处的登记痴呆诊断的发病率和患病率进行了全国性的纵向研究。
所有出生于 1964 年之前且在 40 岁生日时仍在世的丹麦居民，自 40 岁生日或 1970 年 1 月 1 日（以后者为准）开始，随访至首次在医院登记处记录痴呆诊断的日期、移民日期、死亡日期或 2004 年 12 月 31 日（以先到者为准）。计算了年龄和时期特异性痴呆症的发病率和患病率，并与欧洲大型基于社区的队列研究的估计值进行了比较。
研究人群由 4723838 人组成，随访时间为 81090583 人年。1970 年至 2004 年期间共登记了 154152 例痴呆病例。登记的痴呆诊断发病率和患病率呈上升趋势。2003 年，与大型欧洲基于社区的队列研究的估计值相比，年龄标准化发病率比为 0.66。
该研究表明，二级保健部门诊断痴呆症的比率随时间显著提高，并表明该部门可以成为痴呆症患者的重要就诊点。
