Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Int J Oral Maxillofac Surg. 2010 May;39(5):463-8. doi: 10.1016/j.ijom.2010.01.004. Epub 2010 Feb 12.
Calcium phosphate has high osteotransductive potential. The injectable form of calcium phosphate cement (ICAP) can be used as an adjunctive supportive agent for dental implants. The aim of this study was to assess the effect of an ICAP on the reverse torque resistance of titanium implants. Two implant beds (total 24) were prepared in each proximal tibia of 6 beagles. ICAP was injected into one of prepared implant beds (test) and the implant was inserted. The next implant was inserted without ICAP to serve as control. Three dogs were killed after 2 weeks and 3 after 12 weeks. Retrieved implants were subjected to reverse torque test. Results were analyzed with Student's t-test. Scanning electron microscope (SEM) was used for further evaluation. Mean torque values in 2-week healed implants were 52.48 N cm and 50.57 N cm for test and control implants, respectively (p=0.4). 12-week healed implants showed 81.61 N cm and 76.71 N cm for test and control implants, respectively (p=0.14). Results indicated no statistical difference between test and control implants for either healing time. SEM images of tested samples revealed close contact between the bone-ICAP-titanium surface. ICAP must be tested on further developed experimental models.
磷酸钙具有较高的骨诱导潜力。可注射型磷酸钙骨水泥（ICAP）可用作牙种植体的辅助支持剂。本研究旨在评估 ICAP 对钛种植体抗反转扭矩的影响。在 6 只比格犬的每块胫骨近端制备两个种植床（共 24 个）。将 ICAP 注入其中一个准备好的种植床（实验组）并插入种植体。下一个种植体不使用 ICAP 作为对照插入。3 只狗在 2 周和 12 周后被处死。取出的种植体进行反转扭矩测试。采用 Student's t 检验进行分析。扫描电子显微镜（SEM）用于进一步评估。愈合 2 周的种植体的平均扭矩值分别为实验组 52.48 Ncm 和对照组 50.57 Ncm（p=0.4）。愈合 12 周的种植体的平均扭矩值分别为实验组 81.61 Ncm 和对照组 76.71 Ncm（p=0.14）。结果表明，两种愈合时间的实验组和对照组之间没有统计学差异。测试样本的 SEM 图像显示骨-ICAP-钛表面之间存在紧密接触。必须在进一步开发的实验模型上对 ICAP 进行测试。
