Sedgwick D M, Barton J R, Hamer-Hodges D W, Nixon S J, Ferguson A
Gastro-Intestinal Unit, University of Edinburgh, UK.
Br J Surg. 1991 Feb;78(2):176-8. doi: 10.1002/bjs.1800780213.
A geographically based cohort of 37 children with ulcerative colitis has been derived by sampling from Scottish Hospital In-patient Statistics. Surgical histories were examined and analysed by actuarial methods, and the major operations performed were compared with operations for ulcerative colitis in the Lothians' Surgical Audit. Fourteen of the 37 patients had a total of 26 operations (15 major, 11 minor). Sixteen per cent had major surgery within 5 years of onset of symptoms, and the types of operation were similar to those recorded in Lothians' Surgical Audit. Operation rate was significantly lower than that for a parallel cohort of patients with Crohn's disease. With a mean follow-up of 7.4 years, seven (19 per cent) patients have a permanent stoma and there has been one death.
通过对苏格兰医院住院统计数据进行抽样，得出了一个基于地理位置的37例溃疡性结肠炎患儿队列。采用精算方法检查和分析手术史，并将所实施的主要手术与洛锡安外科审计中溃疡性结肠炎的手术进行比较。37例患者中有14例共接受了26次手术（15次大手术，11次小手术）。16%的患者在症状出现后5年内接受了大手术，手术类型与洛锡安外科审计中记录的相似。手术率显著低于平行的克罗恩病患者队列。平均随访7.4年，7例（19%）患者有永久性造口，并有1例死亡。
