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检测和遗传分析健康 Lusitano 马中产万古霉素耐药肠球菌(vanA 型)菌株。

Detection and genetic characterisation of vanA-containing Enterococcus strains in healthy Lusitano horses.

机构信息

Veterinary Science Department, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal.

出版信息

Equine Vet J. 2010 Mar;42(2):181-3. doi: 10.2746/042516409X480386.

DOI:10.2746/042516409X480386
PMID:20156257
Abstract

Lusitano horses were investigated in order to detect the presence of vancomycin-resistant enterococci. vanA isolates showed high level vancomycin (Minimum inhibitory concentration; MIC > or = 128 mg/l) and teicoplanin resistance (MIC 64 mg/l), as well as resistance to ciprofloxacin, erythromycin and tetracycline. The tet(L) and erm(B) genes, associated with tetracycline and erythromycin resistance, respectively, were found in all vanA isolates. The intestinal tract of Lusitano horses can be a potential reservoir for vanA-containing enterococci.

摘要

为了检测耐万古霉素肠球菌的存在,对 Lusitano 马进行了调查。vanA 分离株表现出高水平的万古霉素(最小抑菌浓度;MIC >或= 128 毫克/升)和替考拉宁耐药性(MIC 64 毫克/升),以及对环丙沙星、红霉素和四环素的耐药性。与四环素和红霉素耐药性相关的 tet(L)和 erm(B)基因在所有 vanA 分离株中均被发现。Lusitano 马的肠道可能是携带 vanA 的肠球菌的潜在储库。

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