Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Meyer 113, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Psychiatr Clin North Am. 2010 Mar;33(1):141-58. doi: 10.1016/j.psc.2009.11.001.
Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.
强迫症是一种常见的使人衰弱的疾病,影响个体从儿童期到成年期。有充分证据表明遗传因素对其病因学有贡献,但环境风险因素也可能涉及其中。这种疾病可能具有复杂的遗传模式。分子研究已经确定了几个潜在相关的基因,但还需要更多的研究来确定该疾病的明确病因。