McNamara Patrick, Holtgraves Thomas, Durso Raymon, Harris Erica
Boston University School of Medicine and VA Boston Healthcare System, Boston, MA 02130.
J Neurolinguistics. 2010 Mar 1;23(2):162. doi: 10.1016/j.jneuroling.2009.12.003.
We examined potential neurocognitive mechanisms of indirect speech in support of face management in 28 patients with Parkinson's disease (PD) and 32 elderly controls with chronic disease. In experiment 1, we demonstrated automatic activation of indirect meanings of particularized implicatures in controls but not in PD patients. Failure to automatically engage comprehension of indirect meanings of indirect speech acts in PD patients was correlated with a measure of prefrontal dysfunction. In experiment 2, we showed that while PD patients and controls offered similar interpretations of indirect speech acts, PD participants were overly confident in their interpretations and unaware of errors of interpretation. Efficient reputational adjustment mechanisms apparently require intact striatal-prefrontal networks.
我们研究了28名帕金森病（PD）患者和32名患有慢性疾病的老年对照者中支持面部管理的间接言语的潜在神经认知机制。在实验1中，我们证明了在对照者中特定含义隐含的间接意义会自动激活，但在PD患者中则不会。PD患者未能自动理解间接言语行为的间接意义与前额叶功能障碍的一项指标相关。在实验2中，我们表明，虽然PD患者和对照者对间接言语行为的解释相似，但PD参与者对自己的解释过度自信，并且没有意识到解释错误。有效的声誉调整机制显然需要完整的纹状体 - 前额叶网络。
