多植物提取物还是单植物提取物对坦桑尼亚的局部愈合最有效？
Multi-plant or single-plant extracts, which is the most effective for local healing in Tanzania?
作者信息
Otieno Joseph Nicolao, Hosea Kennedy Macha Matengo, Lyaruu Herbert Valentine, Mahunnah Rogasian Lemmy Anselm
机构信息
Institute of Traditional Medicine, Muhimbili University College of Health and Allied Sciences; P.O.Box 65001 Dar es Salaam, Tanzania.
出版信息
Afr J Tradit Complement Altern Med. 2008 Jan 22;5(2):165-72. doi: 10.4314/ajtcam.v5i2.31269.
Use of multi-plant extracts against infectious diseases is increasing in rural Tanzania. The study evaluated this ethnomedicinal practice by using mixed root extracts of Carisa edulis, Ximenia caffra, Harrisonia abyssinica and Euclea natalensis against single extracts of the same plants. Disc diffusion assay and Tube dilution techniques were used to compare bioactivity of plant extracts in-vitro. The ANOVA test indicated significant difference (P < 0.05) between these extracts types. Multi-plant extracts had inhibition zones of up to 26 mm as compared to 14 mm for single extracts. Minimum Inhibitory Concentration for multi-plant extract was 8.3 microg/ml against 69 microg/ml for single extracts. Multi-plant extracts inhibited all the five test bacterial species while single extracts inhibited three species. Eight out of ten multi-plant extracts (80%) were bactericidal while only two out of four single extracts (50%) were bactericidal. Generally, multi-plant extracts were more superior over single plant extracts and could be developed into more potent antibiotics against resistant pathogens.
在坦桑尼亚农村地区，使用多种植物提取物治疗传染病的情况日益增多。该研究通过使用埃氏假虎刺、南非西门木、阿比西尼亚滨枣和纳塔尔真核木的混合根提取物与这些植物的单一提取物进行对比，对这种民族药用做法进行了评估。采用纸片扩散法和试管稀释技术在体外比较植物提取物的生物活性。方差分析测试表明这些提取物类型之间存在显著差异（P < 0.05）。与单一提取物14毫米的抑菌圈相比，多种植物提取物的抑菌圈可达26毫米。多种植物提取物的最低抑菌浓度为8.3微克/毫升，而单一提取物为69微克/毫升。多种植物提取物对所有五种测试细菌均有抑制作用，而单一提取物只抑制三种。十种多种植物提取物中有八种（80%）具有杀菌作用，而四种单一提取物中只有两种（50%）具有杀菌作用。总体而言，多种植物提取物比单一植物提取物更具优势，有望开发出更有效的抗耐药病原体抗生素。
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