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白叶蒙迪亚水提取物和己烷提取物对性经验不足的雄性大鼠性行为及一些生育参数的影响。

Effects of the aqueous and hexane extracts of Mondia whitei on the sexual behaviour and some fertility parameters of sexually inexperienced male rats.

作者信息

Watcho Pierre, Zelefack Fabien, Nguelefack Télesphore Benoît, Ngouela Silvère, Telefo Phelix Bruno, Kamtchouing Pierre, Tsamo Etienne, Kamanyi Albert

机构信息

Animal Physiology and Phytopharmacology Laboratory, Faculty of Science, University of Dschang, Box 67 Dschang, Cameroon.

出版信息

Afr J Tradit Complement Altern Med. 2006 Aug 28;4(1):37-46. doi: 10.4314/ajtcam.v4i1.31190.

Abstract

The effects of Mondia whitei Hook (Skeels) were studied on the sexual behaviour and some fertility parameters of sexually inexperienced male rats. Animals were orally administered 100 mg/kg and 500 mg/kg of body weight (b.w) of either the aqueous or the hexane extracts of Mondia whitei whilst the control group received 10 mL/kg b.w of 0.3% Tween 80 once/day for 14 days. Their sexual behaviour was monitored on days 0, 1, 7 and 14 days of treatment and 14 days post-treatment. Some fertility parameters (index libido, quantal pregnancy, fertility index) of the treated rat were evaluated on day 13 of treatment by pairing it overnight with two proestrus females. Results showed that Mondia whitei extracts significantly (p<0.001) reduced the mount latency and the hexane extract was found to be more efficient than the aqueous extract. The treatment had no significant effect (p>0.05) on intromission, ejaculation and erection. The fertility of the animals remained unaffected. It's concluded that Mondia whitei had sexual enhancement of the sexually inexperienced male rats.

摘要

研究了白叶蒙迪亚(Mondia whitei Hook (Skeels))对性经验不足的雄性大鼠性行为和一些生育参数的影响。给动物口服白叶蒙迪亚水提取物或己烷提取物,剂量分别为100毫克/千克体重和500毫克/千克体重,而对照组每天接受10毫升/千克体重的0.3%吐温80,持续14天。在治疗的第0、1、7和14天以及治疗后14天监测它们的性行为。在治疗的第13天,将治疗后的大鼠与两只动情前期雌性大鼠过夜配对,评估其一些生育参数(性欲指数、定量妊娠、生育指数)。结果表明,白叶蒙迪亚提取物显著(p<0.001)缩短了爬跨潜伏期,且发现己烷提取物比水提取物更有效。该治疗对插入、射精和勃起无显著影响(p>0.05)。动物的生育能力未受影响。得出的结论是,白叶蒙迪亚对性经验不足的雄性大鼠有性增强作用。

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