Department of Virology, Toyama Institute of Health, 17-1 Imizu-shi, Toyama 939-0363, Japan.
J Clin Microbiol. 2010 Apr;48(4):1215-22. doi: 10.1128/JCM.02130-09. Epub 2010 Feb 17.
A molecular biological survey on porcine norovirus (NoV) and sapovirus (SaV) was conducted in Toyama Prefecture, Japan, during fiscal year 2008. Both NoV and SaV were detected from swine fecal samples throughout the surveillance period, indicating that these viruses were circulating in this region. NoV strains detected in this study belonged to three genotypes that are known as typical swine NoVs. Although human NoVs were occasionally detected, it was unclear whether they replicated in pigs. As for SaV, genogroup VII (GVII) and other divergent genogroups were identified in addition to the dominant genogroup, GIII, which is the prototypic porcine SaV. In addition, 3 strains genetically related to human SaV were detected. Two of these 3 strains were closely related to human SaV GV. Our study showed that genetic diversification of porcine SaV is currently progressing in the swine population.
2008 财年，在日本富山县进行了猪诺如病毒（NoV）和星状病毒（SaV）的分子生物学调查。在整个监测期间，均从猪粪便样本中检测到了 NoV 和 SaV，表明这些病毒在该地区流行。本研究中检测到的 NoV 株属于三种已知的典型猪 NoV 基因型。虽然偶尔也检测到人类 NoV，但尚不清楚它们是否在猪体内复制。至于 SaV，除了占主导地位的 GIII 基因型（原型猪 SaV）外，还鉴定出了 GVII 基因型和其他分化的基因型。此外，还检测到了与人类 SaV 相关的 3 株基因。这 3 株中的 2 株与人类 SaV GV 密切相关。我们的研究表明，目前猪 SaV 的遗传多样化正在猪群中进行。
