Hoeffler U
J Clin Microbiol. 1977 Dec;6(6):555-8. doi: 10.1128/jcm.6.6.555-558.1977.
The production of chondroitin sulfatase, hyaluronidase, deoxyribonuclease, gelatinase, phosphatase, lecithinase, and hemolysins was examined in 95 strains of Propionibacterium acnes and four related species of anaerobic, respectively, microaerophilic coryneform bacteria (P. avidum, P. lymphophilum, P. granulosum, and Corynebacterium minutissimum). All enzymes could be demonstrated in at least one representative of the species tested. Those Propionibacterium species most frequently found in acne vulgaris lesions, i.e., P. acnes and P. granulosum, proved to be the most active organisms concerning the production of the enzymes tested. P. avidum, on the other hand, showed the highest rate of hemolytic activity.
对95株痤疮丙酸杆菌菌株以及分别属于厌氧、微需氧棒状杆菌的4种相关菌种(嗜丙酸杆菌、嗜淋巴丙酸杆菌、颗粒丙酸杆菌和极小棒状杆菌)进行了硫酸软骨素酶、透明质酸酶、脱氧核糖核酸酶、明胶酶、磷酸酶、卵磷脂酶和溶血素的产生情况检测。在所测试的菌种中,至少有一个代表菌种能检测出所有这些酶。在寻常痤疮皮损中最常发现的丙酸杆菌菌种,即痤疮丙酸杆菌和颗粒丙酸杆菌,被证明是在所测试酶的产生方面最活跃的菌种。另一方面,嗜丙酸杆菌表现出最高的溶血活性。