在戈亚尼亚（巴西）辐射事故中意外接触137铯的一名受试者的染色体畸变频率：四个实验室之间的比对

Frequency of chromosomal aberrations in a subject accidentally exposed to 137Cs in the Goiania (Brazil) radiation accident: intercomparison among four laboratories.

作者信息

Ramalho A T, Nascimento A C, Littlefield L G, Natarajan A T, Sasaki M S

机构信息

Instituto de Radioprotecao e Dosimetria, Comissao Nacional de Energia Nuclear, Rio de Janeiro, Brazil.

出版信息

Mutat Res. 1991 Apr;252(2):157-60. doi: 10.1016/0165-1161(91)90016-2.

DOI:10.1016/0165-1161(91)90016-2

PMID:2017205

Abstract

After the Goiania radiation accident which occurred in Brazil in September 1987, an intercomparison was performed to determine whether different cytogenetic laboratories would score similar frequencies of chromosomal aberrations in cultures of lymphocytes of a highly exposed patient. For this purpose 2 chromosome slides from the subject were scored by 4 laboratories in total. The results were consistently close and confirmed the high frequency of chromosome-type aberrations observed initially in the patient.

摘要

1987年9月在巴西戈亚尼亚发生辐射事故后，进行了一次比对，以确定不同的细胞遗传学实验室对一名高暴露患者淋巴细胞培养物中染色体畸变频率的计分是否相似。为此，来自该患者的2张染色体玻片总共由4个实验室进行计分。结果始终相近，证实了最初在该患者身上观察到的染色体型畸变的高频率。